Upcoming Seminars


28th November 2017 - St Andrews Day Special Invited Seminar 

Profesor Paul Matthews OBE, Associate Director UK Dementia Research Institute, Division of Brain Sciences, Imperial College London

Title: "Using large population-based studies to understand age-related changes in cognition"

Abstract: Healthy brain ageing has been an increasing focus of attention, but a precise definition has been difficult. Large population datasets integrating cognitive performance and clinical data are providing substantial new insights regarding heritable, environmental or lifestyle factors associated with the variation in cognitive performance. Insights into molecular mechanisms underlying some of these contributions and interactions can be assessed well experimentally. The concept that preclinical stages of late life dementias begin even decades before clinical expression of the associated diseases has added a new dimension to characterisation of the ageing brain. Will it become possible to redefine diseases of the brain in terms of their physiological antecedents, much as we diagnose hypertension because of its association with cardiovascular disease and stroke? What will be demanded of diagnostic methods delivering these? 

5.15 pm, Room F21, Department of Psychology, 7 George Square, Edinburgh EH8 9JZ (followed by a drinks reception). This seminar is open to all. Booking is not required. PLEASE NOTE THE SLIGHTLY LATER START TIME.



Previous Seminars


5th September 2017 - 10th Annual Research Day

Keynore speaker 1: Professor Andrew McIntoshCCACE Director Designate

Title: "Depression and psychological resilience: Their causes and consequences"

Abstract: Andrew will present data from the STRADL Wellcome Trust longitudinal study of depression and resilience. He will present new data on known risk factors for depression and psychological resilience to stressful life events and the mechanisms through which these factors confer effects on behaviour.

Keynote speaker 2: Dr James Boardman, Reader and Honorary Consultant in Neonatal Medicine, University of Edinburgh

Title: "Born too soon: Consequences for brain development and neurocognitive outcome"

Abstract: To follow

12noon-5pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (preceded by lunch and posters, and followed by a drinks reception).


This is event is free but you MUST reserve a ticket to attend. Please book through eventbrite at:


6th June 2017

Professor Robert S. WilsonRush Alzheimer's Disease Centre, Rush University, USA

Title: Behavioural correlates of cognitive health in old age

Abstract: With the aging of much of the world population, the number of cognitively disabled persons is expected to substantially increase in the coming decades, underscoring the urgent need for effective interventions. I will present an overall model of late-life cognitive change and consider methodologic challenges confronting research on potentially modifiable risk factors for dementia. I will then discuss two longitudinal clinical-pathological cohort studies (Religious Orders Study, Rush Memory and Aging Project) designed to meet (most of) these challenges. In the remaining time, I will review findings from these studies, including cognitive-pathologic correlations, age-effects, and behavioural measures related to residual variance in trajectories of cognitive change not attributable to dementia related pathologies. Better understanding of the mechanisms underlying these resilience effects may suggest novel approaches to cognitive health maintenance in old age.


5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a drinks reception). This seminar is open to all. Booking is not required.


27th April 2017

Professor Kaarin AnsteyDirector of Centre for Research on Ageing, Health and Wellbeing, Australian National Univeristy



21st February 2017

Professor David Bell, Professor of Economics, Stirling University

Title: "The challenges of setting up a longitudinal panel study in ageing in Scotland"

Abstract: This talk will describe the tortuous path to setting up a longitudinal survey of ageing for Scotland. It will discuss the contents of the Scottish study, HAGIS, highlighting its particular merits and the challenges associated with linking survey responses to administrative data, particularly those relating to health. It will also place HAGIS in the context of the global initiative, led by the National Institute of Aging in the US, to collect evidence on the social, psychological, economic and health status of older people.


5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a drinks reception). This seminar is open to all. Booking is not required.


9th January 2017

Professor Verity Brown, School of Psychology and Neuroscience, St Andrews University

Title: "Banishing the shifty homunculous from the frontal cortex: Attentional set-shifting deficits re-examined"

Abstract: Deficits in cognitive fucntion are found in many psychiatric and neurological diseases and the severity of these deficits, particualrly in schizophrenia, predicts poor outome. Nevertheless, treatments have remained elusive and this is why it is important to understand the precise nature of the impairments and their neural basis. In this talk, I will present evidence, from rate and patients with schizophrenia, that supports the surprising conclusion that cognitive flexibility is not an executive function of the frontal lobes.

5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a drinks reception). This seminar is open to all. Booking is not required.



29th November 2016 - St Andrews Day Special Invited Seminar

Professor Rudi GJ Westendorp, Centre for Healthy Ageing, Faculty of Health and Medical Sciences, University of Copenhagen

Title: "Success in old age"

Abstract: There is a rapidly expanding evidence base indicating that a poorly functioning body - due to the ageing process - directly and indirectly affects the brain, which gives rise to cognitive decline, feelings of depression and a delirious mind. There is also ample clinical evidence that a poor mental condition further worsens the physical state of the body resulting in a negative spiral, especially in socioeconomically poor conditions in which social networkas are small and/or dysfunctional. The accumulation of damage to body and brain however, can be prevented or alleviated with behavioural and medical interventions, some of which are already available but not yet implemented. Thus, it is critical to understand the cues in the physical-, societal-, and professional environment that prevent us from taking up a healthy behaviour and those that trigger people to adopt a healthy lifetsyle.

In this lecture I will make a plea that there is a clear need to complement powerful reductionist laboratory approaches in model systems with explorative and experimental research methodologies in humans, and merge these methodologies with systematic, state-of-the-art data-management and analysis methods to synthesize and generate mechanistic understanding of biological and societal issues from a big-picture-perspective.

5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a drinks reception). This seminar is open to all. Booking is not required.


6th September 2016 - CCACE 9th Annual Research Day: "Reserve and Resilience"

Keynote speaker: Professor Yaakov Stern, Cognitive Neuroscience Division, Columbia University, USA.

Title: Cognitive and brain reserve: Evolving concepts

12noon-5pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (preceded by lunch and posters, and followed by a drinks reception).


All are welcome to attend this free event. BOOKING THROUGH EVENTBRITE IS NOW OPEN. YOU CAN ALSO FIND A FULL PROGRAMME HERE. PLEASE VISIT: If you wish to attend BOTH the lunch and talks, PLUS the evening drinks reception then you MUST book tickets for both events.


10th May 2016

Professor Julie Williams, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University.

Title: Defining the Genetic Architecture of Alzheimer's Disease

Abstract: For seventeen years, the APOE gene was the only known susceptibility gene for late-onset Alzheimer's disease (AD). In 2009, we identified three new genome-wide significant susceptibility genes and through major collaborations (GERAD and IGAP), have now dientified 25 associated loci. These loci are not randomly distributed with respect to their functions; pathway analysis shows significant evidence for clusters of genes implicating ubiquination, endocytosis, cholesterol transport, and immunity. A significant proportion of genetic variation in disease pathology is yet to be detected. Thus, we are investigating rare variants in disease through exome chip and next generation sequencing experiments, which have already identified new AD-protective and AD-risk variants. Combining common and rare variant data will provide us with the most comprehensive risk estiamtes of AD.


Using a polygenic score approach we can identify with 90% accuracy, population groups with the greatest and least biological susceptibility to AD. This method has proved more effective in predicting disease status, than individual, genome-wide significant variants of small/moderate effect. Future studies will establish the specific functional changes that contribute to disease by piloting novel cellular modelling techniques using reprogrammed induced pluripotent stem cells (iPSc) cells from individuals with selected genetic risk profiles. This will allow a variety of cell and animal models to be produced to help understand disease mechanisms, test new drug therapies and produce iPSc as a research resource.

5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a drinks reception). This seminar is open to all.


19th January 2016

Professor Peter Visscher, Centre for Neurogenetics & Statistical Genomics, Queensland brain Institute, University of Queensland.

Title: Genomic epidemiology: Drawing inference on complex traits by combining genetic and genomic data

Abstract: Large datasets with genetic and phenotypic information and smaller sets with -omics data such as gene expression or CpG methylation can be combined to address questions about trait (co)variation and how polymorphisms affect complex traits. Such data can also be leveraged to prioritise likely causal pathways for disease. I will give an example of using genome-wide gene expression, gene methylation and genotype data to detect the likely gene targets from GWAS signals and examples of phenotypic prediction from genetic and genomic data.

5.00 pm, Room G.04, 50 George Square, Edinburgh EH8 9JZ (followed by a drinks reception). This seminar is open to all. Please note the change of venue for this seminar. 


24th November 2015 - St Andrews Day invited lecture

Professor Pat Rabbitt, University of Oxford.

Title: Death, intelligence, fun and contentment in old age

Abstract: Many large and reliable longitudinal studies now allow us to explore the relationships between how the extent to which we can keep our wits about us in old age, our past and present health, our nearness to death, the pleasure we get from hobbies, interests and social life, and our general level of contentment interact and determine each other. The talk will discuss how the results of analyses completed this year illustrate these relationships.

5pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a drinks reception). This seminar is open to all.


1st September 2015 - CCACE 8th Annual Research Day

Room F21, 7 George Square, Edinburgh EH8 9JZ. This event is open to all. Please register at eventbrite (

Keynote speaker: Professor Katri Raikkonen, Institute of Behavioural Sciences, University of Helsinki.

Title: Early life origins of psychological development and mental health

Research Day Programme:

11.30am-12noon: Screening of the LBC film "The Living Brain"

12noon-1.00pm: Lunch and poster sesson

1.00pm: Welcome from CCACE Director

1.15pm: Keynote presentation

2.15pm: Presentations from CCACE collaborators

3.00pm-3.30pm: Tea/coffee break

3.30pm: Presentations from CCACE Research Groups

5.00pm: Closing remarks from CCACE Director

5.15pm: Drinks reception


16th June 2015

Professor Nick Fox, Dementia Research Centre, Institute of Neurology, London.

Title: Imaging the onset and progression of neurodegeneration: Prospects for prevention?

Abstract: There is now consistent evidence to suggest that there is a long and detectable preclinical period to a number of neurodegenerative diseases including Alzheimer's disease. Although the exact sequence and time course of biomarker and imaging changes in these diseases are unclear, in Alzheimer's disease, cerebral amyloid deposition appears to predate neurodegeneration and clinical decline by more than a decade. Hippocampal and brain atrophy rates becomes abnormal much closer to symptoms with pathological rates of loss evident around five years before clinical diagnosis.

As a result of this, and motivated by recent failures of Phase III trials in mild to moderate Alzheimer's disease, there is increased interest in undertaking trials at a much earlier stage in the disease - when less irreversible neuronal loss has taken place and there is more to save - perhaps even before individuals have any cognitive symptoms. The first trials in presymptomatic familial and sporadic AD are underway and further studies are planned. Similarly there are now a number of initatives in other neurodegenerative diseases such as frontotemporal dementia or Huntington's disease where treatments will be trialed in presymptomatic or very early disease. Designing such "prevention" trials raises a number of challenges including how best to identify subjects for inclusion, how to assess how near to symptoms they are and how to assess progression. Imaging and biomarkers will have important roles to play in meeting these challenges.

5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a drinks reception). This seminar is open to all.


24th February 2015

Professor Simon Lovestone, Professor of Translational Neuroscience, Department of Psychiatry, Medical Sciences Division, University of Oxford.

Title Alzheimer's disease: big problem, Big Data, big solution?

Abstract: The growing numbers of people with dementia, Alzheimer's disease in particular, presents challenges not only to older people themselves, and to their families, but also to health services and indeed to economies. It's no wonder therefore that politicians have made this a priority area for development. Yet just as, after many years of under-funding, attention is focussed on neurodegeneration, the first trials of putative disease modification therapeutics have reported negative results and drug development looks increasingly difficult in these diseases. This is a very big problem. Might Big Data provide something of a solution or is it a big, albeit fashionable, distraction?

Some evidence suggests that Big Data - whether derived from biological or from clinical datasets - might help progress the search for therapeutic interventions in dementia. Research using informatics as a core component will be described both in the field of molecular biomarkers for clinical trial utility and in turning mechanistic understanding into drug development programmes. Then platforms for dementia research utilising large variable datasets - essentially Big Data platforms - will be described including in drug discovery, the Dementias Platform UK and the Innovative Medicines Initiatives - the European Medical Information Framework and the European Prevention of Alzheimer's Disease programme.

5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a drinks reception). This seminar is open to all.


25th November 2014, ST ANDREW'S DAY LECTURE

Professor George Davey-Smith, Professor of Clinical Epidemiology, MRC Integrative Epidemiology Unit, University of Bristol.

Title: Mendelian randomisation in the multi-omic world

2.30pm, Edinburgh Centre for Carbon Innovation, Old High School, Infirmary Street, Edinburgh EH1 1LZ (followed by a drinks reception). This seminar followed on from the epigenetics discussion day at the same venue.


7th October 2014

Professor Karen Ritchie, Professor of Epidemiology, Department of Public Health and Epidemiology, Imperial College London.

Title: Putting your money where your mouth is: can we design programmes to prevent Alzheimer's disease?

Abstract: Once considered an inevitable part of ageing, the dementias are now recognised as pathologies distinct from the normal brain ageing process.

Consequently over the past three decades both clinical and epidemiological studies have aimed to demonstrate risk factors specific to dementia, notably Alzheimer's disease. Of the large number of significant risk and protective factors which have been found, many of these are potentially reversible and statistical modelling suggests that reducing exposure may have an even greater impact on future disease incidence than altering genetic predisposition. Most of these exposures occur in middle-age suggesting the need for a life-time approach, intervention strategies which target younger populations and a reconsideration of Alzheimer's disease clinical criteria.

5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a drinks reception).


27th August 2014, 7th CCACE ANNUAL RESEARCH DAY

Keynote speaker: Professor Paul Thompson, Imaging Genetics Centre, University of Southern California, Los Angeles.

Title: The ENIGMA Project: Investigating brain diseases with imaging and genetics in 29,000 people

Abstract: The ENIGMA project unites 185 institutions worldwide with genoma-wide scans (GWAS), brain MRI and DTI (from N=29,000 participants) to discover (1) global patterns in how 9 major diseases affect the brain, (2) genomic and environmental factors that "help or harm" the brain, and (3) factors that promote or disrupt brain integrity and brain networks. ENIGMA's disease-related working groups study schizophrenia, bipolar disorder, major depression, ADHD, and additions, revealing patterns of brain differences, how they vary worldwide, and how medicaitons and other factors affect them.

Genome-wide analysis of brain data makes it possible to discover which genetic variants may disrupt or re-wire the brain. The ENIGMA Project has now found and replicated genomic regions associated with regional brain structure (Stein, 2012, Hibar et al, submitted); we also present new data implicating some of the same genomic regions in psychosis and mental retardation, and joint work with the Psychiatric Genomics Consortium, and Alzheimer's disease and epilepsy consortia, to follow up genetic discoveries rapidly and in new ways. Genome-wide conntectome-wide scans now reveal genetic variants that affect brain organisation, and some may be promising targets to treat neurodegeneration (Jahanshad, 2013). We also report updates from the ENIGMA's working groups, that have uncovered unsuspected patterns in disease profiles, by integrating neuroimaging and genetics on a worldwide scale. We also discuss some mathematical "Big Data" challenges in imaging genomics, related to the Bell's number, combinatorics, and code-breaking.

References: Stein, J.L. +207 authors. (2012). Identification of common variants associated with human hippocampal and intracranial volumes. Nature Genetics, 44(5), 55261.

Jahanshad, N. et al (2013). Genome-wide scane of healthy human connectome discovers SPON1 gene variant influencing dementia severity. Proceedings of the National Academy of Sciences USA, 110(12), 476873.

Thompson, P.M. +307 authors. (2014). The ENIGMA Consotrium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behaviour. Available at

The day was exceptionally well attended and also included CCACE updates and exciting talks from our young researchers. Topics included psychological distress and mortality, episodic memory, bilingualism, brain imaging, processing speed, delirium and cognitive decline, and DNA methylation. And, if that is not enough, there was a film premiere, posters and a free, tasty lunch.

12 noon - 5.30pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a drinks reception).


13th May 2014

Professor Andrew Steptoe, British Heart Foundation Professor of Psycholohy and Director, Institute of Epidemiology and Health Care, University College London.

"Psychobiology of health and disease: Integrating laboratory and population studies"

Abstract: There is considerable evidence that social and psychological factors contribute to chronic physical disease risk and health outcomes such as premature mortality. Psychobiology in this context refers to the processes through which psychosocial factors activate autonomic, neuroendocrine, immunological and inflammatory systems in ways that can be either health damaging or health protective. Several types of study and research methdology are involved in exploring these processes, ranging from laboratory experiments on physiological responses to stressful situations, through naturalistic studies of biological function in everyday life, to large-scale longitudinal population of studies of health and disease. The convergence of these methodologies will be illustrated through recent research on factors such as social isolation, loneliness and hostility in relation to physical health outcomes.

5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a wine reception).


26th November 2013, ST ANDREW'S DAY LECTURE

Professor Randall Engle, Professor of Psychology, School of Psychology, Georgia Tech, USA, and Department of Psychology, University of Edinburgh.

"Working memory capacity as a mediating variable"

Abstract: Working memory capacity (WMC) has the qualities of a trait, with identifiable brain structures, neurotransmitters, and genetic factors associated with individual differences. This trait is associated with individual differences in working memory capacity. This trait is associated with performance in a huge array of real world tasks from complex learning, to mind wandering, to the prevention of intrusive thought. WMC can also be thought of as a state variable in that many conditions can lead to a reduction in trait WMC. Some examples are sleep deprivation, drugs and stereotype threat. I argue for a model in which WMC at the construct level is a mediating variable for many different tasks in which control of attention is important.

5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a wine reception). This seminar is open to all.


8th October 2013

Dr Colm Cunningham, Institute of Neuroscience, Trinity College Dublin.

5.00 pm, Room S1 (PLEASE NOTE THE CHANGE OF ROOM), 7 George Square, Edinburgh EH8 9JZ (followed by a wine reception).This seminar is open to all. Entrance is on a first come first served basis.


3rd September 2013, 6th ANNUAL RESEARCH DAY


PLANS FOR 2013-2018

Keynote lecture: Professor Sudha Seshadri, Professor of Neurology, Boston University Alzheimer's Disease Center, USA.

"Genetic determinants of cognition, dementia and Alzheimer's disease: An epidemiological perspective"

1.15pm - 5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ.

CCACE begins its second quinquennium on 1st September 2013. To mark the occasion please join us for our Annual Research Day on the 3rd September which this year will be dedicated to showcasing our plans for the next 5 years, 2013-2018.

This half day meeting will provide the opportunity to hear first-hand what our CCACE researchers plan to focus on across the next 5 years. Come and hear about our new and exciting research plans and also some of our brand new early findings. The afternoon will begin with lunch at 12.15pm and a keynote presentation from Professor Sudha Seshadri from the Alzheimer's Disease Center at Boston University will kick of the presentations at 1.15pm. This is an excellent opportunity to hear from our Director and senior Research Group Leaders on how CCACE will move forward to 2018. A drinks reception in the concourse of the Department of Psychology at 5.00pm will round off the afternoon.

This event is free and open to all. Lunch is 12.15-1.15pm, talks are 1.15-5.00pm and the drinks reception is 5.00-7.00pm. Please register for the talks, lunch and drinks reception separately.

Confirmed speakers

Keynote: Professor Sudha Seshadri, Alzheimer's Disease Center, Boston University

Professor Ian Deary, CCACE Director, Department of Psychology, University of Edinburgh

Professor David Batty, Department of Epidemiology and Public-Health, University College London

Professor Robert Logie, Department of Psychology, University of Edinburgh

Professor Alasdair MacLullich, Division of Geriatric Medicine, University of Edinburgh

Professor David Porteous, MRC Centre for Inflammation Research, University of Edinburgh

Professor Joanna Wardlaw, Centre for In Vivo Imaging Sciences, University of Edinburgh

Dr Robin Morton, CCACE Knowledge Exchange Officer, University of Edinburgh


5th June 2013 (please note the change of date)

Professor Jonathan Flint, Professor of Molecular Psychiatry, Wellcome Trust Centre for Human Genetics, University of Oxford.

"The genetic analyis of depression"

5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a wine reception).This seminar is open to all.


16th April 2013

Dr John Gallacher, Institute of Primary Care and Public Health, Cardiff University.

5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a wine reception). This seminar is open to all.


12th February 2013

Professor Hugh Perry
, Professor of Experimental Neuropathology, Centre for Biological Sciences, University of Southampton.

5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by a wine reception).This seminar is open to all. Click here for the poster advert.

The impact of systemic inflammation on the brain in health and disease

It is now well recognized that during progression of neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and prion diseases there is an innate immune response in the brain. This innate immune response is characterised by an increase in the density and activation of the microglia, as seen by the alterations in their morphology and the upregulation or de novo synthesis of macrophage antigens.  The contribution of these activated microglia to disease progression is at present unclear.  To investigate this problem we have studied murine prion disease as a tractable laboratory model of chronic progression neurodegeneration.  We have shown that early in the disease the microglia become morphologically activated but have an anti-inflammatory phenotype.  We demonstrated that systemic inflammation can have a profound impact on the phenotype of these microglia that appear to be ‘primed’ by the ongoing neurodegeneration.  Systemic inflammation switches them from an anti-inflammatory to a pro-inflammatory phenotype with exacerbation of symptoms and an increased rate of progression of disease.  We have investigated the molecules that might be involved in priming the microglia during chronic neurodegeneration. We have then gone on to study the impact of systemic inflammation in patients with Alzheimer’s disease: the data show that systemic inflammation and infections are associated with more rapid cognitive decline and exacerbation of symptoms. Understanding how systemic co-morbidities contribute to disease progression offers a route to slowing disease progression and improving the quality of life of those with neurodegenerative disease.


30th November 2012, ST ANDREWS DAY LECTURE

Professor Archana Singh-Manoux, Centre for Research in Epidemiology & Population Health, INSERM, Paris

5.00pm, Room F21, 7 George Square, Edinburgh EH8 9JZ (preceeded by a wine reception at 4.15pm) 


4 September 2012, 5th ANNUAL RESEARCH DAY

Keynote Lecture: Dr Denise Park, The Centre for Vital Longevity, University of Texas at Dallas

1.00 pm - 5.00 pm. Room F21, 7 George Square, Edinburgh EH8 9JZ (followed by wine reception).


8 May 2012, SEMINAR
'The Remarkable Plasticity of Ageing'

Professor Kaare Christensen, Department of Public Health, The Danish Ageing Research Centre.
5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ. This seminar is open to all and will be followed by a wine reception.


14 February 2012, SEMINAR
'Epidemiological Neuropathology of Brain Ageing'

Professor Paul Ince, Department of Neuroscience, University of Sheffield.
5.00 pm, Room F21, 7 George Square, Edinburgh EH8 9JZ. This seminar is open to all and will be followed by a wine reception.


30 November 2011.· ST ANDREWS DAY LECTURE 2011
'Striving for science and policy relevant research for our ageing populations'

Professor Carol Brayne, Department of Public Health and Primary Care, University of Cambridge.


6 September 2011. 4th Annual Research Day.  
Keynote Lecture: Professor Ulman Lindenberger
, Max Planck Institute for Human Development, Germany. 'Older brains are not all alike: heterogeneity in cognitive ageing'.  


‘Cognition and the Genome’
Professor Seth Grant,
Sanger Institute, University of Cambridge.



26 April 2011.· 'Aging, memory, and cortical overrecruitment: how are they related?'· Professor Michael Rugg. Center for Vital Longevity, University of Texas at Dallas.
Gaddum Lecture Theatre, 1 George Square, Edinburgh.



18 April 2011.·· 'Decomposing cognitive change: longitudinal study of cognition across the lifespan'.
Professor Tim Salthouse,
The Cognitive Aging Laboratory, University of Virginia.




7th September 2010.· 3rd ANNUAL RESEARCH DAY KEYNOTE LECTURE· ‘The changing role of genes in cognitive ageing’
 Professor Nancy Pedersen, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet


7th April 2010 . ‘Causes and consequences of dementia and the contribution of neuroimaging’
or John O’Brien, Institute for Ageing and Health, Newcastle University.



13th May 2010. ‘Memory consolidation: Synaptic tagging and mental schemas’
Professor Richard Morris,
Centre for Cognitive and Neural Systems, University of Edinburgh